Flow cytometry was performed to confirm the effects of A‐CpG (D35) in the A549 lung cancer cell line, and the results showed that the IFN‐γ‐induced expression of PD‐L1 and β2‐MG was reduced after coculture with A‐CpG (D35) (Fig 1b). The gene discussed is IFNG; the disease is lung cancer.