Besides, there is strong evidence that lncRNAs can affect tumour suppressor genes or oncogenes.16 LncRNAs play important roles in gene regulation and affect many aspects of cellular homeostasis,9, 17 and they are closely related to tumour occurrence and development.4, 18 Using the microarray scanning and bioinformatics analyses, we identified a potential tumour metastasis suppressor in CRC, designated as LINC00341. Here, SYNE3 is linked to neoplasm.