Meanwhile, injection of XCL1-OT-I plus poly(I:C) followed by subsequent injection of anti-PD-1 Ab significantly decreased the tumour size at day 23 after tumour inoculation (p < 0.05) and prolonged survival (p < 0.05) than injection of XCL1-OT-I plus poly(I:C) without anti-PD-1 Ab (Fig. 6c). This evidence concerns the gene XCL1 and neoplasm.