TSLP and allergic disease: On the other hand, TSLP is a cytokine known to promote type 2 inflammation in multiple disease settings, including not only asthma and atopic dermatitis, but also food allergy22,43 and eosinophilic esophagitis.20 In addition, two clinical studies using an anti-TSLP antibody have shown promising results for asthma without major side effects.13,14 Therefore, the use of anti-TSLP antibody is a promising treatment option for allergic diseases by blocking the activation of multiple immune cell cascades as we identified here.