Our data support the suggestion that the IL-10/IL-6 ratio is a diagnostic marker of IOL23,24 because the IL-10 level was about 620-fold, 4.0-fold, and 7.8-fold higher and the IL-6 level was about 8.2-fold, 210-fold, and 710-fold lower in IOL than in sarcoidosis, ARN, and BE, respectively (Table 3). Here, IL10 is linked to Barrett esophagus.