We determined the saturation point of maraviroc (MVC) on the recombinant viruses by treating them with varying concentrations of 10-fold serial dilutions starting from 1 × 104 nM and going down to 1 × 10−3 nM in a single-round infection assay in TZM-bl and GHOST (3) CCR5+ (Hi-5) cells. This evidence concerns the gene CCR5 and infection.