Immunoblot and qPCR analysis of primary leukemia cells from both MA9 or MA9-Foxm1-CKO recipient mice revealed that β-catenin protein level but not mRNA levels were dramatically decreased in MA9-Foxm1-CKO BM cells as compared to MA9 BM cells (Fig. 6f and Supplementary Fig. 7b). This evidence concerns the gene FOXM1 and leukemia.