SGCG and limb-girdle muscular dystrophy: Skeletal muscle pathology of the gamma-sarcoglycan (Sgcg)-null mouse model (Box 1) of limb-girdle muscular dystrophy (LGMD) is worse in a DBA2/J than a 129/SVemst/J genetic background (Fukada et al., 2010; Heydemann et al., 2009).