However, if the lack of increased cancer risk in these patients is due to a compensatory factor that develops in the presence of germline activated FGFR3, and if this compensatory factor is attenuated in the presence of FGFR inhibitors given during early life stages, it would be important to take into consideration the theoretical possibility of a later cancer risk if these FGFR3 inhibitors were discontinued [193]. Here, FGFR3 is linked to cancer.