CCK and Anxiety: Prenatal exposure in rodents causes an increased rate of ultrasonic vocalizations when separated from the mother, which leads to increased levels of anxiety that are related to the presence of CB1 receptors in the cortex, the hippocampus, the lateral septum, the nucleus accumbens and the amygdala, which regulate the release of 5-HT, dopamine, CCK and CRF, which are anxiogenic peptides [13, 21].