Moreover, Zinc-doped iron oxide nanoparticles modified with polyethylenimine molecules and dimercaptosuccinic acid in combination with radiotherapy prolonged survival of CT-2A mouse glioma model and were mainly incorporated by TAM/MDSCs, although the definition of these cell populations was based only on CD45 and CD11b markers without further characterization [34]. This evidence concerns the gene PTPRC and central nervous system cancer.