In contrast, Orleans reeler mice have a transcriptional reelin product with a 220‐bp deletion within the seventh and eighth reelin repeats and potentially express a truncated reelin.11, 12 Our novel Reln‐del mice more faithfully reflect the Japanese subject with the RELN deletion compared with our previous study using Orleans reeler mice.17 In addition, we generated the Reln‐del mice in the C57BL/6J strain that is commonly used for behavior studies in schizophrenia models, distinct from Orleans reeler mice, which were maintained in the Balb/c strain. Here, RELN is linked to schizophrenia.