IL5 and Alzheimer disease: In addition, expanded ILC2 (GATA3hi) associated with human AD (Kim, 2015; Salimi et al., 2013; Roediger et al., 2014), and their capacity to produce the type 2 cytokines IL-5 and/or IL-13, was recapitulated in Sox13-/- mice (Figure 1G, Figure 1—figure supplement 1E–G).