GPT and Recurrent upper respiratory tract infections: The most common AEs, occurring in > 10% of patients overall, were viral upper respiratory tract infection (Cohort 1: n = 1 [4.5%], Cohort 2: n = 4 [36.4%]), headache (Cohort 1: n = 3 [13.6%], Cohort 2: n = 2 [18.2%]), and increased ALT or AST (Cohort 1: n = 2 [9.1%], Cohort 2: n = 2 [18.2%], for each of these AEs).