Here we examined, in a blinded, case-control study, whether a low DNA Repair score, calculated from the DNA Repair enzymatic activities of OGG1 (8-oxoguanine DNA glycosylase), MPG (methylpurine DNA glycosylase), and APE1 (apurinic/apyrimidinic endonuclease 1) (also known as OMA score), all of which act primarily on oxidative DNA damage, is a risk biomarker for lung cancer in the United Kingdom as it was in the Israeli population (23,25–27). The gene discussed is MPG; the disease is lung carcinoma.