SCs displayed increased expression of MMP-2, MMP-9, and MMP-12 at the protein level after co-cultivation with cervical cancer cells, whereas no change in the expression of these MMPs was detected in HeLa and ME-180 cells, differing from previous report about pancreatic adenocarcinoma cells (23) (Figure 2C, Supplementary Figure 3C). This evidence concerns the gene MMP2 and cervical cancer.