The triple combination treatment of exercise+RT+PD-1 blockade was associated with significantly slower tumor growth compared to the dual combination of RT+PD-1 blockade (Exercise+RT+aPD-1: 203 ± 52 mm3 vs sedentary+RT+aPD-1: 325 ± 83 mm3; p < 0.01 Figure 4A–4B). Here, PDCD1 is linked to neoplasm.