Characteristic vessel wall remodeling in aneurysms was demonstrated by EVG staining, and continuous and wavy elastic lamellae could be found in saline-treated Apoe−/− and Apoe−/− IKKε−/− mice (Figure 2(h)), as well as degradation of elastin filaments in both in Ang II-treated mice. The gene discussed is IKBKE; the disease is aneurysm.