Considering the potential for galectins as cancer treatment targets, clinical trials using galectin inhibitors have already started for both galectins 1 (ClinicalTrials.gov identifier: NCT01724320—for advanced solid tumors; NCT00054977—for advanced solid tumors in combination or not with 5-Fluorouracil) and 3 (NCT02575404—for advanced melanoma, non-small cell lung cancer, and head and neck squamous cell cancer in combination with Pembrolizumab; NCT02117362—for advanced melanoma in combination with Ipilimumab). The gene discussed is LGALS1; the disease is melanoma.