Furthermore, a recent study revealed that DCN repressed corneal stromal fibroblasts migration via inducing EGFR degradation (Figure 3C) (Mohan et al., 2019), which has not been well investigated in the context of skin wounds, although low levels of DCN and increased activation of the MARK1/3 signaling have been observed in keloid tissues (Meenakshi et al., 2009). The gene discussed is DCN; the disease is keloid.