PGF and preeclampsia: Recently, a prediction model for early-onset preeclampsia was developed, which included the sFlt-1/PlGF ratio plus mean arterial pressure, being parous, and previous preeclampsia; this model was superior to those using the sFlt-1/PlGF ratio alone or with mean UtA-PI.26 Consistent with these findings, Gómez-Arriaga et al33 showed the sFlt-1/PlGF ratio is superior to Doppler for predicting preeclampsia in women with singleton pregnancies and suspected or confirmed preeclampsia.