This approach would be consistent with the updated 2019 guideline of the German, Swiss and Austrian Societies of Obstetrics and Gynecology for hypertensive disorders in pregnancy, where combined new-onset hypertension plus altered angiogenic status (increased sFlt-1/PlGF ratio or decreased PlGF alone) not accounted for by alternative diagnoses is recognized as preeclampsia.17 Moreover, we suggest that the term preeclampsia should be evolved to angiogenic-placental syndrome. Here, PGF is linked to hypertensive disorder.