Yang et al. verified that cZNF292 silencing repressed glioma proliferation and cell cycle progression via the Wnt/β-catenin pathway, moreover, they also proved that the transcription factors E2F1, NF-κB, HIF-1, AP-1, STAT3 and STAT5 expression markedly down-regulated after cZNF292 silencing, suggesting that the potential mechanism of NF-κB and STAT3/5 pathways by cZNF292 [92]. The gene discussed is NFKB1; the disease is central nervous system cancer.