Furthermore, in RAW264.7 cells, SAHA significantly reduced the expression of TNF‐α and IL‐6 in macrophages after LPS stimulation;34 TSA also reduced the IL‐1β level in the serum of a mice model of post‐influenza pneumonia but, interestingly, the acetylation level of histone H3 was not affected.35 Here, TNF is linked to pneumonia.