CD73 has been reported to be an important predictor of poor prognosis in several cancers.10, 11, 12, 13 To investigate the prognostic relevance of CD73 expression in EGFR mutation‐positive NSCLC patients untreated with ICIs, we further screened 67 patients with stage I‐III EGFR mutation‐positive NSCLC who had undergone complete resection. This evidence concerns the gene NT5E and cancer.