Our findings corroborate those of previous studies.18, 20, 21, 22, 23, 24 Additionally, the cellular expressions of podocyte components (ie ZO‐1, synaptopodin) and endothelial cell surface marker (ie CD31+) were preserved, whereas renal tubular injury biomarker (ie KIM‐1) was substantially reduced in CKD animals treated by iPS‐MSCs than in CKD only animals. This evidence concerns the gene SYNPO and chronic kidney disease.