Alzheimer's disease (AD) is a progressive neurodegenerative disease leading to dementia, which is characterized by extracellular neuritic plaques containing amyloid‐β (Aβ) peptide deposition and intracellular neurofibrillary tangles consisting of hyperphosphorylated tau protein (Davis & Chisholm, 1999; Goedert et al., 1996). This evidence concerns the gene MAPT and Alzheimer disease.