Besides learning and memory deficits, patients with AD are often accompanied by depression, and laboratory research has shown that TRPV1 activation may affect anxiogenic responses and depression‐related behaviors (Abdelhamid, Kovacs, Nunez, & Larson, 2014; Kasckow, Mulchahey, & Geracioti, 2004). This evidence concerns the gene TRPV1 and depressive disorder.