Ectopic expression of miR‐378 greatly increased cell proliferation by inversely regulating KLF9.18 In melanoma, Sun et al found that miR‐378 expression was significantly upregulated in cancerous tissues, miR‐378 overexpression markedly stimulated oncogenic behaviors of cancer cells both in vitro and in vivo through regulating FOXN3.19 Ma et al reported that miR‐378 upregulation significantly promoted the proliferation, migration, and invasion capacity of liver cancer cells by downregulating Fus expression.20 This evidence concerns the gene FOXN3 and cancer.