Thus, we conducted a proteomic study in NPC of 3 ASD patients and 3 control individuals and found that two differentially expressed proteins in ASD NPC, EWSR1 (Panova = 0.02, fold change = 1.48) and APP (Panova = 0.04, fold change = 1.5), are upstream regulators of a significant number of MNeu1-turquoise genes (Fig. 4; p < 0.05, see Supplementary Table S11). Here, EWSR1 is linked to nasopharyngeal carcinoma.