STAT3 and glioblastoma: Our experiments with inhibition of JAK2/STAT3 pathway (utilizing AG490, a JAK2 inhibitor, and STAT3 inhibitor-6) demonstrated STAT3-dependent pro-surviving functions in CBD-targeted GBM cells (see Fig. 4f–h) and substantial change in the live-death balance at the CBD-induced conditions in the presence of STAT3 inhibitors.