CUX2 and neuroblastoma: CUX2 is not induced by retinoic acid in 11 different NB cell lines (Supplementary Fig. 11 and Data 10) so the mechanism of partial rescue by retinoic acid is distinct from that of CUX2. Combining NAC with ectopic expression of CUX2 did not significantly increase survival over NAC or CUX2 alone (Supplementary Fig. 11B).