However, in the normal cell model (C2C12), CASZ1 regulates gene sets associated with repression of oligodendrocyte differentiation, telomere maintenance and chromosome maintenance, while in the tumor model (SMS-CTR cells) the top regulated gene sets are involved in breast cancer development, colorectal cancer development, cervical cancer proliferation (Supplementary Data 8). This evidence concerns the gene CASZ1 and breast cancer.