In support of this possibility, it was recently shown that treatment of cancer cells with IFN-γ altered the processing and length of peptides loaded on MHC proteins [38]: since IFN-γ is a potent inducer of autophagy [39], it is possible that autophagy may alter the immunogenicity of epitopes expressed by cells, rendering infected cells more visible to the immune system. This evidence concerns the gene IFNG and cancer.