IL17A and systemic lupus erythematosus: As anti-IL-17A antibody therapy, we developed a DNA vaccine in this study to induce an anti-IL-17A antibody to treat SLE, since our previous reports successfully documented the development of therapeutic B cell vaccines to neutralize autoantibodies against targets such as angiotensin II [8] and DPP (Dipeptidyl Peptidase)-IV [9].