In this study, we showed an increase in the adipogenic differentiation potential of lipedema ASCs isolated from SVF-T and SVF-A, as assessed by the degree of lipid droplet accumulation by Oil Red O stain and the expression of the main adipogenic gene markers: adiponectin, LPL, CD36, Leptin, PPAR-γ and Glut4. The gene discussed is LPL; the disease is Lipedema.