Although Oligo-Fucoidan treatment did not affect the distributions of the p53−/− cancer cells and the p53+/+ cancer cells in the cell cycle (Supplementary Figure S6B,C), cisplatin induced sub-G1 populations, a sign of apoptosis with reduced DNA content, more in the p53+/+ cells (57.5%) (Supplementary Figure S6C) than in the p53−/− cells (9.2%) (Supplementary Figure S6B). This evidence concerns the gene TP53 and cancer.