Besides the findings of Rulina that knockdown of Cand1 induces apoptosis in PCa, our findings of reduced cell proliferation due to Cand1 knockdown are also in line with a recent study in liver cancer where Che et al. showed that Cand1 was overexpressed in cancerous issues compared to the corresponding adjacent benign ones and that high expression of Cand1 was associated with poor OS [35,40]. Here, CAND1 is linked to posterior cortical atrophy.