The work of the Cancer Genome Atlas classification of PTC [4] has identified two molecular signatures: (i) BRAF p.V600E-like typical of classic/conventional PTC and (ii) RAS-like typical of the encapsulated follicular variant PTC, a tumor type with features that overlaps with other follicular patterned tumors, such as follicular thyroid adenoma and carcinoma [2,4,5]. The gene discussed is BRAF; the disease is neoplasm.