Flavanone hesperetin induced cytochrome c release, activation of caspases-3 and -9, and reduced Bax to Bcl-2 ratio in gastric cancer cells [100], in the Eca109 cell line [62] as well as in the HT-29, MCF-7, and MDA-MB-231 cell lines [64,101]. Here, BCL2 is linked to gastric cancer.