CD56 is highly sensitive to NE cells [4]; however, it is also detectable in a heterogeneous group of non-NE neoplasms, including nephroblastoma, neuroblastoma, myeloid, lymphoid, and plasma cell tumors, as well as in hepatocellular, renal cell, ovarian, endometrial, and thyroid carcinomas [25,26]. The gene discussed is NCAM1; the disease is neuroblastoma.