NFATC2 and Epstein-Barr virus infection: These results reveal that a major phenotypic difference between T1 EBV- versus T2 EBV- infected B cells is increased lytic viral infection in T2 EBV-infected cells and suggest that this altered phenotype is due to not only the universal presence of the Zp-V3 form of Zp in T2 EBV strains, but also enhanced NFATc1/NFATc2 activity in B cells with T2 EBV infection.