CRP and syphilis: In the ULISSE study, a controlled trial that has evaluated the benefits of a standardized strategy for the etiologic diagnosis of uveitis [16], we prospectively assessed the costs of a standardized approach, in which all patients had a minimal work-up regardless of the type of uveitis (CBC, ESR, C-reactive protein, tuberculin skin test, syphilis serology, and chest X-ray) followed by more complex investigations, ordered by ophthalmologists, if needed.