Brisk cases were significantly enriched in BC (p-val = 0.041), TIM3+cDC1 (p-val = 0.024), macrophages (p-val = 0.043) (including the proliferating subgroup (p-val = 0.034)), NK (p-val = 0.011), anergic Tcy (p-val = 0.039) and proliferating Tcy (p-val = 0.006) (Figure 4B). Here, MPPE1 is linked to breast cancer.