Up‐regulation of TUG1 caused by hypertrophic stimulation enhanced its ceRNA action on miR‐34a to alleviate the target regulation of miR‐34a on DKK1 and increase the expression of DKK1, suppressing the activation of Wnt/β‐catenin signalling and relieving cardiac hypertrophy (a schematic diagram shown in Figure 6). Here, DKK1 is linked to cardiac hypertrophy.