For instance, lncRNA ROR (retinoic acid receptor‐related orphan receptor) interacts with miR‐133 to facilitate cardiac hypertrophy.27 LncRNA CHRF (cardiac hypertrophy related factor) induces cardiac hypertrophy through competitively binding miR‐93 to increase AKT3 expression.28 LncRNA CASC15 (cancer susceptibility candidate 15) promotes cardiac hypertrophy through sponging miR‐432‐5p to up‐regulate TLR4 expression.29 We demonstrated that lncRNA TUG1 ameliorated cardiac hypertrophy by sponging miR‐34a. Here, TLR4 is linked to cardiac hypertrophy.