Of these, only Turner syndrome was approved for the brand HUMATROPE. The FDA document states that children with ISS are shorter than average, have adequate secretion of GH and might have an “equivalent degree of short stature” [16, p. 16] and “the same severity of growth failure” [16, p. 28] as the other non-GHD conditions already treated with hGH. The gene discussed is GH1; the disease is Turner syndrome.