MARCKS and colorectal carcinoma: These two cell lines are particularly suitable for the functional characterization of MARCKS in the CRC context, since LoVo cells completely lack MARCKS expression owing to a genomic deletion (Bickeböller et al. 2015; Rombouts et al. 2013) and HT-29 cells show heavily phosphorylated MARCKS (Bickeböller et al. 2015) (Fig. 2c, d).