In addition, the mRNA expression levels of U-II and GPR14 were found to be increased in various human tumor cells, including HeLa cervical cancer cells, BeWo choriocarcinoma cells, IMR-32 neuroblastoma cells, and VMRC-RCW human renal cell carcinoma cells [33, 34]. The gene discussed is UTS2R; the disease is hereditary clear cell renal cell carcinoma.