SAPCD2 and melanoma: Recently, several studies have reported that SAPCD2 is overexpressed in several kinds of solid tumors, including GC, hepatocellular carcinoma (HCC), melanoma, glioblastoma, and renal cell cancer (RCC) [2, 6–9], and might play important roles in cell proliferation, migration, and invasion by activating JAK/STAT, MAPK, and Wnt signaling pathways [3, 4, 7, 9].