Among the 81 proteins consistently deregulated by nitroxoline treatment and relevant in cancer biology, three were selected for western blot validation, namely the ATP1B3 subunit of Na/K-ATPase pump, β-catenin (CTNNB1) and transferrin receptor protein 1 (TFRC) (Table 1 and Fig. 2A). Here, ATP1B3 is linked to cancer.