In total, we analysed the expression of six pro-apoptotic (Bax, Bak, Smac, Procaspase-9, Apaf-1, Procaspase-3) and three antiapoptotic proteins (Bcl-2, Bcl-xL, XIAP) in metastatic melanoma samples spotted on TMAs. This evidence concerns the gene BAK1 and metastatic melanoma.