Although La, the founding member of the Larp family, was first discovered as an auto-antigen in individuals with lupus erythromatosis and Sjögren's syndrome, and genetic variation of LARP1, LARP4A, LARP4B and LARP7 are observed in cancers, the role of LARP6 in human disease is as yet unclear (Maraia et al., 2017). The gene discussed is LARP1; the disease is Sjogren syndrome.